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The NLRP3–inflammasome as a sensor of organelle dysfunction

Diverse pathogen- and damage-associated stresses drive inflammation via activation of the multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are integrated by the cell to regulate NLRP3 has been the subject of intense research, and yet an accepted unifying hypothesis for t...

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Detalles Bibliográficos
Autores principales:	Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543090/ https://www.ncbi.nlm.nih.gov/pubmed/33044555 http://dx.doi.org/10.1083/jcb.202006194

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