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Targeted cyclooxygenase-2 inhibiting nanomedicine results in pain-relief and differential expression of the RNA transcriptome in the dorsal root ganglia of injured male rats
Chronic constriction injury of the sciatic nerve in rats causes peripheral neuropathy leading to pain-like behaviors commonly seen in humans. Neuropathy is a leading cause of neuropathic pain, which involves a complex cellular and molecular response in the peripheral nervous system with interactions...
Autores principales: | Stevens, Andrea M, Saleem, Muzamil, Deal, Brooke, Janjic, Jelena, Pollock, John A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543154/ https://www.ncbi.nlm.nih.gov/pubmed/32762277 http://dx.doi.org/10.1177/1744806920943309 |
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