Cargando…

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

BACKGROUND: Prognostic tools are required to guide clinical decision-making in COVID-19. METHODS: We studied the relationship between the ratio of interleukin (IL)-6 to IL-10 and clinical outcome in 80 patients hospitalized for COVID-19, and created a simple 5-point linear score predictor of clinica...

Descripción completa

Detalles Bibliográficos
Autores principales:	McElvaney, Oliver J, Hobbs, Brian D, Qiao, Dandi, McElvaney, Oisín F, Moll, Matthew, McEvoy, Natalie L, Clarke, Jennifer, O'Connor, Eoin, Walsh, Seán, Cho, Michael H, Curley, Gerard F, McElvaney, Noel G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543971/ https://www.ncbi.nlm.nih.gov/pubmed/33039714 http://dx.doi.org/10.1016/j.ebiom.2020.103026

Ejemplares similares

Corrigendum to ‘A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19’
por: McElvaney, Oliver J, et al.
Publicado: (2020)

Alpha-1 antitrypsin for cystic fibrosis complicated by severe cytokinemic COVID-19
por: McElvaney, Oliver J, et al.
Publicado: (2021)

Interleukin-6: obstacles to targeting a complex cytokine in critical illness
por: McElvaney, Oliver J, et al.
Publicado: (2021)

Reply to Blot et al. and to Inoue et al.
por: McElvaney, Oliver J., et al.
Publicado: (2021)

Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients
por: Palmas, Francesco, et al.
Publicado: (2021)

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients
por: Clarke, Jennifer, et al.
Publicado: (2021)

Diagnosing α(1)-antitrypsin deficiency: how to improve the current algorithm
por: McElvaney, Noel G.
Publicado: (2015)

A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19
por: McElvaney, Oliver J., et al.
Publicado: (2022)

Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis
por: McQuillan, Karen, et al.
Publicado: (2020)

The prevalence of liver abnormalities in individuals with ZZ Alpha-1 Antitrypsin deficiency
por: McElvaney, OF, et al.
Publicado: (2015)

Adult and Adolescent Disclosures of Child Sexual Abuse: A Comparative Analysis
por: McGill, Lucy, et al.
Publicado: (2022)

Editorial: Novel Anti-Inflammatory Approaches for Cystic Fibrosis Lung Disease: Identification of Molecular Targets and Design of Innovative Therapies
por: Ribeiro, Carla Maria Pedrosa, et al.
Publicado: (2021)

Is There a Therapeutic Role for Selenium in Alpha-1 Antitrypsin Deficiency?
por: Greene, Catherine M., et al.
Publicado: (2013)

Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency
por: McLean, Caitriona, et al.
Publicado: (2009)

Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications
por: McElvaney, Oisin F., et al.
Publicado: (2022)

Inhibition of Toll-Like Receptor 2-Mediated Interleukin-8 Production in Cystic Fibrosis Airway Epithelial Cells via the α7-Nicotinic Acetylcholine Receptor
por: Greene, Catherine M., et al.
Publicado: (2010)

Coeliac disease: clinical presentations, correlations of dietary compliance, symptomatic response and repeat biopsy findings.
por: McElvaney, N. G., et al.
Publicado: (1992)

MicroRNAs in inflammatory lung disease - master regulators or target practice?
por: Oglesby, Irene K, et al.
Publicado: (2010)

The role of TIM-containing molecules in airway disease and their potential as therapeutic targets
por: Vega-Carrascal, Isabel, et al.
Publicado: (2012)

Alpha-1 antitrypsin regulates neutrophil reactive oxygen species production via inhibition of key players of the respiratory burst oxidase system
por: Alfawaz, Bader, et al.
Publicado: (2013)

The importance of CFTR expression for neutrophil function in patients with Cystic Fibrosis
por: Jundi, B, et al.
Publicado: (2015)

Perceiving threat in others: The role of body morphology
por: McElvaney, Terence J., et al.
Publicado: (2021)

Identifying criminals: No biasing effect of criminal context on recalled threat
por: McElvaney, Terence J., et al.
Publicado: (2022)

Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis
por: Reeves, Emer P., et al.
Publicado: (2012)

An investigation of IL-8 degradation in response to PA401 compared to hypertonic saline in bronchoalveolar lavage fluid of Cystic Fibrosis patients
por: Kerr, H, et al.
Publicado: (2015)

Adolescents’ experiences of psychotherapy following child sexual abuse
por: McElvaney, Rosaleen, et al.
Publicado: (2023)

Exploring the views of healthcare professionals on increasing smoking cessation advice for patients
por: Ho, ShuYing, et al.
Publicado: (2013)

Dysregulated neutrophil function in individuals with alpha-1 antitrypsin deficiency caused by modified membrane cholesterol content.
por: Jundi, Bakr, et al.
Publicado: (2015)

Alpha-1 proteinase inhibitors for the treatment of alpha-1 antitrypsin deficiency: safety, tolerability, and patient outcomes
por: Chotirmall, Sanjay H, et al.
Publicado: (2015)

Pleural Fluid Analysis: Standstill or a Work in Progress?
por: Hassan, T., et al.
Publicado: (2012)

A survey of the prevalence of smoking and smoking cessation advice received by in patients in two teaching hospitals in Ireland
por: Ohakim, AL, et al.
Publicado: (2015)

Characterization of the Inflammatory Response to Severe COVID-19 Illness
por: McElvaney, Oliver J., et al.
Publicado: (2020)

The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis
por: Reeves, Emer P., et al.
Publicado: (2011)

Impaired Airway Epithelial Barrier Integrity in Response to Stenotrophomonas maltophilia Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics
por: Molloy, Kevin, et al.
Publicado: (2020)

Preventing depression: Qualitatively examining the benefits of depression-focused iCBT for participants who do not meet clinical thresholds
por: Earley, C., et al.
Publicado: (2017)

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity
por: McGarry, Niamh, et al.
Publicado: (2015)

The impact of alpha-1 antitrypsin augmentation therapy on neutrophil-driven respiratory disease in deficient individuals
por: Dunlea, Danielle M, et al.
Publicado: (2018)

Respiratory epithelial cells require Toll-like receptor 4 for induction of Human β-defensin 2 by Lipopolysaccharide
por: MacRedmond, Ruth, et al.
Publicado: (2005)

Quantification and Evaluation of the Role of Antielastin Autoantibodies in the Emphysematous Lung
por: Low, Teck Boon, et al.
Publicado: (2011)

Alpha-1 antitrypsin augmentation therapy decreases miR-199a-5p, miR-598 and miR-320a expression in monocytes via inhibition of NFκB
por: Hassan, Tidi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fnj3st9nr3e3271vb2286scdns