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Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis

AIM: To investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective. METHODS: During 2009–2013, patients aged 50–74 years with an unstable dorsally displaced distal radius fracture...

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Autores principales: Saving, Jenny, Heintz, Emelie, Pettersson, Hans, Enocson, Anders, Mellstrand Navarro, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544026/
https://www.ncbi.nlm.nih.gov/pubmed/33031472
http://dx.doi.org/10.1371/journal.pone.0240377
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author Saving, Jenny
Heintz, Emelie
Pettersson, Hans
Enocson, Anders
Mellstrand Navarro, Cecilia
author_facet Saving, Jenny
Heintz, Emelie
Pettersson, Hans
Enocson, Anders
Mellstrand Navarro, Cecilia
author_sort Saving, Jenny
collection PubMed
description AIM: To investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective. METHODS: During 2009–2013, patients aged 50–74 years with an unstable dorsally displaced distal radius fracture were randomised to VLP or EF. Primary outcome was the incremental cost-effectiveness ratio (ICER) for VLP compared with EF. Data regarding health effects (Quality-adjusted life years, QALYs) was prospectively collected during the trial period until 3 years after surgery. Cost data was collected retrospectively for the same time period and included direct and indirect costs (production loss). RESULTS: One hundred and thirteen patients (VLP n = 58, EF n = 55) had complete data until 3 years and were used in the analysis. At one year, the VLP group had a mean incremental cost of 878 euros and a gain of 0.020 QALYs compared with the EF group, rendering an ICER of 43 900 euros per QALY. At three years, the VLP group had a mean incremental cost of 1 082 euros and a negative incremental effect of -0.005 QALYs compared to the EF group, which means that VLP was dominated by EF. The probability that VLP was cost-effective compared to EF at three years, was lower than 50% independent of the willingness to pay per QALY. CONCLUSION: Three years after distal radius fracture surgery, VLP fixation resulted in higher costs and a smaller effect in QALYs compared to EF. Our results indicate that it is uncertain if VLP is a cost-effective treatment of unstable distal radius fractures compared to EF.
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spelling pubmed-75440262020-10-19 Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis Saving, Jenny Heintz, Emelie Pettersson, Hans Enocson, Anders Mellstrand Navarro, Cecilia PLoS One Research Article AIM: To investigate the cost-effectiveness of Volar Locking Plate (VLP) compared to External Fixation (EF) for unstable dorsally displaced distal radius fractures in a 3-year perspective. METHODS: During 2009–2013, patients aged 50–74 years with an unstable dorsally displaced distal radius fracture were randomised to VLP or EF. Primary outcome was the incremental cost-effectiveness ratio (ICER) for VLP compared with EF. Data regarding health effects (Quality-adjusted life years, QALYs) was prospectively collected during the trial period until 3 years after surgery. Cost data was collected retrospectively for the same time period and included direct and indirect costs (production loss). RESULTS: One hundred and thirteen patients (VLP n = 58, EF n = 55) had complete data until 3 years and were used in the analysis. At one year, the VLP group had a mean incremental cost of 878 euros and a gain of 0.020 QALYs compared with the EF group, rendering an ICER of 43 900 euros per QALY. At three years, the VLP group had a mean incremental cost of 1 082 euros and a negative incremental effect of -0.005 QALYs compared to the EF group, which means that VLP was dominated by EF. The probability that VLP was cost-effective compared to EF at three years, was lower than 50% independent of the willingness to pay per QALY. CONCLUSION: Three years after distal radius fracture surgery, VLP fixation resulted in higher costs and a smaller effect in QALYs compared to EF. Our results indicate that it is uncertain if VLP is a cost-effective treatment of unstable distal radius fractures compared to EF. Public Library of Science 2020-10-08 /pmc/articles/PMC7544026/ /pubmed/33031472 http://dx.doi.org/10.1371/journal.pone.0240377 Text en © 2020 Saving et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Saving, Jenny
Heintz, Emelie
Pettersson, Hans
Enocson, Anders
Mellstrand Navarro, Cecilia
Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title_full Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title_fullStr Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title_full_unstemmed Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title_short Volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–A 3-year cost-utility analysis
title_sort volar locking plate versus external fixation for unstable dorsally displaced distal radius fractures–a 3-year cost-utility analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544026/
https://www.ncbi.nlm.nih.gov/pubmed/33031472
http://dx.doi.org/10.1371/journal.pone.0240377
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