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The procoagulant activity of tissue factor expressed on fibroblasts is increased by tissue factor-negative extracellular vesicles
Tissue factor (TF) is critical for the activation of blood coagulation. TF function is regulated by the amount of externalised phosphatidylserine (PS) and phosphatidylethanolamine (PE) on the surface of the cell in which it is expressed. We investigated the role PS and PE in fibroblast TF function....
Autores principales: | Rosas, Marcela, Slatter, David A., Obaji, Samya G., Webber, Jason P., Alvarez-Jarreta, Jorge, Thomas, Christopher P., Aldrovandi, Maceler, Tyrrell, Victoria J., Jenkins, Peter V., O’Donnell, Valerie B., Collins, Peter W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544082/ https://www.ncbi.nlm.nih.gov/pubmed/33031441 http://dx.doi.org/10.1371/journal.pone.0240189 |
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