Alleviating chronic ER stress by p38-Ire1-Xbp1 pathway and insulin-associated autophagy in C. elegans neurons

ER stress occurs in many physiological and pathological conditions. However, how chronic ER stress is alleviated in specific cells in an intact organism is an outstanding question. Here, overexpressing the gap junction protein UNC-9 (Uncoordinated) in C. elegans neurons triggers the Ire1-Xbp1-mediat...

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Detalles Bibliográficos
Autores principales: Guan, Liying, Zhan, Zhigao, Yang, Yongzhi, Miao, Yue, Huang, Xun, Ding, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544145/
https://www.ncbi.nlm.nih.gov/pubmed/32986702
http://dx.doi.org/10.1371/journal.pgen.1008704

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