DNA targeting by subtype I-D CRISPR–Cas shows type I and type III features

Prokaryotic CRISPR–Cas immune systems are classified into six types based on their effector complexes which cleave dsDNA specifically (types I, II and V), ssRNA exclusively (type VI) or both ssRNA via a ruler mechanism and ssDNA unspecifically (type III). To date, no specific cleavage of ssDNA targe...

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Detalles Bibliográficos
Autores principales: Lin, Jinzhong, Fuglsang, Anders, Kjeldsen, Anders Lynge, Sun, Kaiyan, Bhoobalan-Chitty, Yuvaraj, Peng, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544194/
https://www.ncbi.nlm.nih.gov/pubmed/32960267
http://dx.doi.org/10.1093/nar/gkaa749

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