The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae

Spn1/Iws1 is a conserved protein involved in transcription and chromatin dynamics, yet its general in vivo requirement for these functions is unknown. Using a Spn1 depletion system in Saccharomyces cerevisiae, we demonstrate that Spn1 broadly influences several aspects of gene expression on a genome...

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Detalles Bibliográficos
Autores principales: Reim, Natalia I, Chuang, James, Jain, Dhawal, Alver, Burak H, Park, Peter J, Winston, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544207/
https://www.ncbi.nlm.nih.gov/pubmed/32941642
http://dx.doi.org/10.1093/nar/gkaa745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544207/
https://www.ncbi.nlm.nih.gov/pubmed/32941642
http://dx.doi.org/10.1093/nar/gkaa745

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