PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response

Poly(ADP-ribosyl)ation regulates numerous cellular processes like genome maintenance and cell death, thus providing protective functions but also contributing to several pathological conditions. Poly(ADP-ribose) (PAR) molecules exhibit a remarkable heterogeneity in chain lengths and branching freque...

Descripción completa

Detalles Bibliográficos
Autores principales: Aberle, Lisa, Krüger, Annika, Reber, Julia M, Lippmann, Michelle, Hufnagel, Matthias, Schmalz, Michael, Trussina, Irmela R E A, Schlesiger, Sarah, Zubel, Tabea, Schütz, Karina, Marx, Andreas, Hartwig, Andrea, Ferrando-May, Elisa, Bürkle, Alexander, Mangerich, Aswin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544232/
https://www.ncbi.nlm.nih.gov/pubmed/32667640
http://dx.doi.org/10.1093/nar/gkaa590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544232/
https://www.ncbi.nlm.nih.gov/pubmed/32667640
http://dx.doi.org/10.1093/nar/gkaa590

Ejemplares similares