A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection

BACKGROUND: Real-time reverse transcription-PCR (rRT-PCR) has been the most effective and widely implemented diagnostic technology since the beginning of the COVID-19 pandemic. However, fuzzy rRT-PCR readouts with high Ct values are frequently encountered, resulting in uncertainty in diagnosis. METH...

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Detalles Bibliográficos
Autores principales: Huang, Weiren, Yu, Lei, Wen, Donghua, Wei, Dong, Sun, Yangyang, Zhao, Huailong, Ye, Yu, Chen, Wei, Zhu, Yongqiang, Wang, Lijun, Wang, Li, Wu, Wenjuan, Zhao, Qianqian, Xu, Yong, Gu, Dayong, Nie, Guohui, Zhu, Dongyi, Guo, Zhongliang, Ma, Xiaoling, Niu, Liman, Huang, Yikun, Liu, Yuchen, Peng, Bo, Zhang, Renli, Zhang, Xiuming, Li, Dechang, Liu, Yang, Yang, Guoliang, Liu, Lanzheng, Zhou, Yunying, Wang, Yunshan, Hou, Tieying, Gao, Qiuping, Li, Wujiao, Chen, Shuo, Hu, Xuejiao, Han, Mei, Zheng, Huajun, Weng, Jianping, Cai, Zhiming, Zhang, Xinxin, Song, Fei, Zhao, Guoping, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544594/
https://www.ncbi.nlm.nih.gov/pubmed/33045467
http://dx.doi.org/10.1016/j.ebiom.2020.103036

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