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SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden

SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies a...

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Autores principales: Rudberg, Ann-Sofie, Havervall, Sebastian, Månberg, Anna, Jernbom Falk, August, Aguilera, Katherina, Ng, Henry, Gabrielsson, Lena, Salomonsson, Ann-Christin, Hanke, Leo, Murrell, Ben, McInerney, Gerald, Olofsson, Jennie, Andersson, Eni, Hellström, Cecilia, Bayati, Shaghayegh, Bergström, Sofia, Pin, Elisa, Sjöberg, Ronald, Tegel, Hanna, Hedhammar, My, Phillipson, Mia, Nilsson, Peter, Hober, Sophia, Thålin, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544689/
https://www.ncbi.nlm.nih.gov/pubmed/33033249
http://dx.doi.org/10.1038/s41467-020-18848-0
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author Rudberg, Ann-Sofie
Havervall, Sebastian
Månberg, Anna
Jernbom Falk, August
Aguilera, Katherina
Ng, Henry
Gabrielsson, Lena
Salomonsson, Ann-Christin
Hanke, Leo
Murrell, Ben
McInerney, Gerald
Olofsson, Jennie
Andersson, Eni
Hellström, Cecilia
Bayati, Shaghayegh
Bergström, Sofia
Pin, Elisa
Sjöberg, Ronald
Tegel, Hanna
Hedhammar, My
Phillipson, Mia
Nilsson, Peter
Hober, Sophia
Thålin, Charlotte
author_facet Rudberg, Ann-Sofie
Havervall, Sebastian
Månberg, Anna
Jernbom Falk, August
Aguilera, Katherina
Ng, Henry
Gabrielsson, Lena
Salomonsson, Ann-Christin
Hanke, Leo
Murrell, Ben
McInerney, Gerald
Olofsson, Jennie
Andersson, Eni
Hellström, Cecilia
Bayati, Shaghayegh
Bergström, Sofia
Pin, Elisa
Sjöberg, Ronald
Tegel, Hanna
Hedhammar, My
Phillipson, Mia
Nilsson, Peter
Hober, Sophia
Thålin, Charlotte
author_sort Rudberg, Ann-Sofie
collection PubMed
description SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and May 8th 2020, which was higher than the reported regional seroprevalence during the same time period. Symptoms associated with seroprevalence were anosmia (odds ratio (OR) 28.4, 95% CI 20.6–39.5) and ageusia (OR 19.2, 95% CI 14.3–26.1). Seroprevalence was also associated with patient contact (OR 2.9, 95% CI 1.9–4.5) and covid-19 patient contact (OR 3.3, 95% CI 2.2–5.3). These findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers. Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community.
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spelling pubmed-75446892020-10-19 SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden Rudberg, Ann-Sofie Havervall, Sebastian Månberg, Anna Jernbom Falk, August Aguilera, Katherina Ng, Henry Gabrielsson, Lena Salomonsson, Ann-Christin Hanke, Leo Murrell, Ben McInerney, Gerald Olofsson, Jennie Andersson, Eni Hellström, Cecilia Bayati, Shaghayegh Bergström, Sofia Pin, Elisa Sjöberg, Ronald Tegel, Hanna Hedhammar, My Phillipson, Mia Nilsson, Peter Hober, Sophia Thålin, Charlotte Nat Commun Article SARS-CoV-2 may pose an occupational health risk to healthcare workers. Here, we report the seroprevalence of SARS-CoV-2 antibodies, self-reported symptoms and occupational exposure to SARS-CoV-2 among healthcare workers at a large acute care hospital in Sweden. The seroprevalence of IgG antibodies against SARS-CoV-2 was 19.1% among the 2149 healthcare workers recruited between April 14th and May 8th 2020, which was higher than the reported regional seroprevalence during the same time period. Symptoms associated with seroprevalence were anosmia (odds ratio (OR) 28.4, 95% CI 20.6–39.5) and ageusia (OR 19.2, 95% CI 14.3–26.1). Seroprevalence was also associated with patient contact (OR 2.9, 95% CI 1.9–4.5) and covid-19 patient contact (OR 3.3, 95% CI 2.2–5.3). These findings imply an occupational risk for SARS-CoV-2 infection among healthcare workers. Continued measures are warranted to assure healthcare workers safety and reduce transmission from healthcare workers to patients and to the community. Nature Publishing Group UK 2020-10-08 /pmc/articles/PMC7544689/ /pubmed/33033249 http://dx.doi.org/10.1038/s41467-020-18848-0 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Rudberg, Ann-Sofie
Havervall, Sebastian
Månberg, Anna
Jernbom Falk, August
Aguilera, Katherina
Ng, Henry
Gabrielsson, Lena
Salomonsson, Ann-Christin
Hanke, Leo
Murrell, Ben
McInerney, Gerald
Olofsson, Jennie
Andersson, Eni
Hellström, Cecilia
Bayati, Shaghayegh
Bergström, Sofia
Pin, Elisa
Sjöberg, Ronald
Tegel, Hanna
Hedhammar, My
Phillipson, Mia
Nilsson, Peter
Hober, Sophia
Thålin, Charlotte
SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title_full SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title_fullStr SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title_full_unstemmed SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title_short SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden
title_sort sars-cov-2 exposure, symptoms and seroprevalence in healthcare workers in sweden
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544689/
https://www.ncbi.nlm.nih.gov/pubmed/33033249
http://dx.doi.org/10.1038/s41467-020-18848-0
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