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Impact of non-proteinogenic amino acids in the discovery and development of peptide therapeutics
With the development of modern chemistry and biology, non-proteinogenic amino acids (NPAAs) have become a powerful tool for developing peptide-based drug candidates. Drug-like properties of peptidic medicines, due to the smaller size and simpler structure compared to large proteins, can be changed f...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544725/ https://www.ncbi.nlm.nih.gov/pubmed/32945974 http://dx.doi.org/10.1007/s00726-020-02890-9 |