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Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies

Toll-like receptors (TLRs) are at the forefront of pathogen recognition ensuring host fitness and eliciting protective cellular and humoral responses. Signaling pathways downstream of TLRs are tightly regulated for preventing collateral damage and loss of tolerance toward commensals. To trigger effe...

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Detalles Bibliográficos
Autores principales:	Belhaouane, Imène, Hoffmann, Eik, Chamaillard, Mathias, Brodin, Priscille, Machelart, Arnaud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544743/ https://www.ncbi.nlm.nih.gov/pubmed/33072109 http://dx.doi.org/10.3389/fimmu.2020.569127

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