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Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

The role of fibroblasts in tissue fibrosis has been extensively studied. Activated fibroblasts, namely myofibroblasts, produce pathological extracellular matrix. CD248, a type I transmembrane glycoprotein, is expressed in fibroblasts after birth. In human chronic kidney disease, upregulated CD248 in...

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Detalles Bibliográficos
Autores principales:	Pai, Chen-Hsueh, Lin, Shu-Rung, Liu, Chia-Hao, Pan, Szu-Yu, Hsu, Hao, Chen, Yi-Ting, Yen, Ching-Tzu, Yu, I-Shing, Wu, Hua-Lin, Lin, Shuei-Liong, Lin, Shu-Wha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544830/ https://www.ncbi.nlm.nih.gov/pubmed/33033277 http://dx.doi.org/10.1038/s41598-020-73194-x

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