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Upregulation of Mcl-1S Causes Cell-Cycle Perturbations and DNA Damage Accumulation

As an important regulator of apoptosis, Mcl-1 protein, a member of the Bcl-2 family, represents an attractive target for cancer treatment. The recent development of novel small molecule compounds has allowed Mcl-1-inhibitory therapy to proceed to clinical trials in cancer treatment. However, the pos...

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Detalles Bibliográficos
Autores principales:	Streletskaia, Alena Y., Senichkin, Viacheslav V., Prikazchikova, Tatiana A., Zatsepin, Timofei S., Zhivotovsky, Boris, Kopeina, Gelina S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544834/ https://www.ncbi.nlm.nih.gov/pubmed/33072738 http://dx.doi.org/10.3389/fcell.2020.543066

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