Ouabain Suppresses IL-6/STAT3 Signaling and Promotes Cytokine Secretion in Cultured Skeletal Muscle Cells

The cardiotonic steroids (CTS), such as ouabain and marinobufagenin, are thought to be adrenocortical hormones secreted during exercise and the stress response. The catalytic α-subunit of Na,K-ATPase (NKA) is a CTS receptor, whose largest pool is located in skeletal muscles, indicating that muscles...

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Detalles Bibliográficos
Autores principales: Pirkmajer, Sergej, Bezjak, Katja, Matkovič, Urška, Dolinar, Klemen, Jiang, Lake Q., Miš, Katarina, Gros, Katarina, Milovanova, Kseniya, Pirkmajer, Katja Perdan, Marš, Tomaž, Kapilevich, Leonid, Chibalin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544989/
https://www.ncbi.nlm.nih.gov/pubmed/33101052
http://dx.doi.org/10.3389/fphys.2020.566584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544989/
https://www.ncbi.nlm.nih.gov/pubmed/33101052
http://dx.doi.org/10.3389/fphys.2020.566584

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