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Ouabain Suppresses IL-6/STAT3 Signaling and Promotes Cytokine Secretion in Cultured Skeletal Muscle Cells
The cardiotonic steroids (CTS), such as ouabain and marinobufagenin, are thought to be adrenocortical hormones secreted during exercise and the stress response. The catalytic α-subunit of Na,K-ATPase (NKA) is a CTS receptor, whose largest pool is located in skeletal muscles, indicating that muscles...
Autores principales: | Pirkmajer, Sergej, Bezjak, Katja, Matkovič, Urška, Dolinar, Klemen, Jiang, Lake Q., Miš, Katarina, Gros, Katarina, Milovanova, Kseniya, Pirkmajer, Katja Perdan, Marš, Tomaž, Kapilevich, Leonid, Chibalin, Alexander V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7544989/ https://www.ncbi.nlm.nih.gov/pubmed/33101052 http://dx.doi.org/10.3389/fphys.2020.566584 |
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