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Convolutional neural network-based models for diagnosis of breast cancer

Breast cancer is the most prevailing cancer in the world and each year affecting millions of women. It is also the cause of largest number of deaths in women dying in cancers. During the last few years, researchers are proposing different convolutional neural network models in order to facilitate di...

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Detalles Bibliográficos
Autores principales: Masud, Mehedi, Eldin Rashed, Amr E., Hossain, M. Shamim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545025/
https://www.ncbi.nlm.nih.gov/pubmed/33052172
http://dx.doi.org/10.1007/s00521-020-05394-5
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author Masud, Mehedi
Eldin Rashed, Amr E.
Hossain, M. Shamim
author_facet Masud, Mehedi
Eldin Rashed, Amr E.
Hossain, M. Shamim
author_sort Masud, Mehedi
collection PubMed
description Breast cancer is the most prevailing cancer in the world and each year affecting millions of women. It is also the cause of largest number of deaths in women dying in cancers. During the last few years, researchers are proposing different convolutional neural network models in order to facilitate diagnostic process of breast cancer. Convolutional neural networks are showing promising results to classify cancers using image datasets. There is still a lack of standard models which can claim the best model because of unavailability of large datasets that can be used for models’ training and validation. Hence, researchers are now focusing on leveraging the transfer learning approach using pre-trained models as feature extractors that are trained over millions of different images. With this motivation, this paper considers eight different fine-tuned pre-trained models to observe how these models classify breast cancers applying on ultrasound images. We also propose a shallow custom convolutional neural network that outperforms the pre-trained models with respect to different performance metrics. The proposed model shows 100% accuracy and achieves 1.0 AUC score, whereas the best pre-trained model shows 92% accuracy and 0.972 AUC score. In order to avoid biasness, the model is trained using the fivefold cross validation technique. Moreover, the model is faster in training than the pre-trained models and requires a small number of trainable parameters. The Grad-CAM heat map visualization technique also shows how perfectly the proposed model extracts important features to classify breast cancers.
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spelling pubmed-75450252020-10-09 Convolutional neural network-based models for diagnosis of breast cancer Masud, Mehedi Eldin Rashed, Amr E. Hossain, M. Shamim Neural Comput Appl S.I. : Healthcare Analytics Breast cancer is the most prevailing cancer in the world and each year affecting millions of women. It is also the cause of largest number of deaths in women dying in cancers. During the last few years, researchers are proposing different convolutional neural network models in order to facilitate diagnostic process of breast cancer. Convolutional neural networks are showing promising results to classify cancers using image datasets. There is still a lack of standard models which can claim the best model because of unavailability of large datasets that can be used for models’ training and validation. Hence, researchers are now focusing on leveraging the transfer learning approach using pre-trained models as feature extractors that are trained over millions of different images. With this motivation, this paper considers eight different fine-tuned pre-trained models to observe how these models classify breast cancers applying on ultrasound images. We also propose a shallow custom convolutional neural network that outperforms the pre-trained models with respect to different performance metrics. The proposed model shows 100% accuracy and achieves 1.0 AUC score, whereas the best pre-trained model shows 92% accuracy and 0.972 AUC score. In order to avoid biasness, the model is trained using the fivefold cross validation technique. Moreover, the model is faster in training than the pre-trained models and requires a small number of trainable parameters. The Grad-CAM heat map visualization technique also shows how perfectly the proposed model extracts important features to classify breast cancers. Springer London 2020-10-09 2022 /pmc/articles/PMC7545025/ /pubmed/33052172 http://dx.doi.org/10.1007/s00521-020-05394-5 Text en © Springer-Verlag London Ltd., part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle S.I. : Healthcare Analytics
Masud, Mehedi
Eldin Rashed, Amr E.
Hossain, M. Shamim
Convolutional neural network-based models for diagnosis of breast cancer
title Convolutional neural network-based models for diagnosis of breast cancer
title_full Convolutional neural network-based models for diagnosis of breast cancer
title_fullStr Convolutional neural network-based models for diagnosis of breast cancer
title_full_unstemmed Convolutional neural network-based models for diagnosis of breast cancer
title_short Convolutional neural network-based models for diagnosis of breast cancer
title_sort convolutional neural network-based models for diagnosis of breast cancer
topic S.I. : Healthcare Analytics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545025/
https://www.ncbi.nlm.nih.gov/pubmed/33052172
http://dx.doi.org/10.1007/s00521-020-05394-5
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