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An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma

We report a rare case with the late occurrence of growing teratoma syndrome (GTS). A 24-year-old woman with Grade 3 immature teratoma of ovary underwent complete surgery and chemotherapy. Nineteen years later, she developed hematuria and pelvic mass that was completely resected and pathology reveale...

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Autores principales: Tantitamit, Tanitra, U'wais, Ala, Huang, Kuan-Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545050/
https://www.ncbi.nlm.nih.gov/pubmed/33101916
http://dx.doi.org/10.4103/GMIT.GMIT_70_18
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author Tantitamit, Tanitra
U'wais, Ala
Huang, Kuan-Gen
author_facet Tantitamit, Tanitra
U'wais, Ala
Huang, Kuan-Gen
author_sort Tantitamit, Tanitra
collection PubMed
description We report a rare case with the late occurrence of growing teratoma syndrome (GTS). A 24-year-old woman with Grade 3 immature teratoma of ovary underwent complete surgery and chemotherapy. Nineteen years later, she developed hematuria and pelvic mass that was completely resected and pathology revealed mature cystic teratoma. She has regularly followed up with tumor marker and computed tomography every three months. No evidence of disease has been detected throughout 14 years. In addition, we present a brief review of literature of ovarian GTS in the last decade. We have found that advanced stage, high grade, or early recurrence of germ cell tumor (GCT) could be the risk factors of GTS. It tends to appear within 1 year if the patients had the incomplete resection of primary disease. We stress the importance of long-term follow-up after treatment GCT to early recognition and treatment.
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spelling pubmed-75450502020-10-22 An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma Tantitamit, Tanitra U'wais, Ala Huang, Kuan-Gen Gynecol Minim Invasive Ther Case Report We report a rare case with the late occurrence of growing teratoma syndrome (GTS). A 24-year-old woman with Grade 3 immature teratoma of ovary underwent complete surgery and chemotherapy. Nineteen years later, she developed hematuria and pelvic mass that was completely resected and pathology revealed mature cystic teratoma. She has regularly followed up with tumor marker and computed tomography every three months. No evidence of disease has been detected throughout 14 years. In addition, we present a brief review of literature of ovarian GTS in the last decade. We have found that advanced stage, high grade, or early recurrence of germ cell tumor (GCT) could be the risk factors of GTS. It tends to appear within 1 year if the patients had the incomplete resection of primary disease. We stress the importance of long-term follow-up after treatment GCT to early recognition and treatment. Wolters Kluwer - Medknow 2020-08-01 /pmc/articles/PMC7545050/ /pubmed/33101916 http://dx.doi.org/10.4103/GMIT.GMIT_70_18 Text en Copyright: © 2020 Gynecology and Minimally Invasive Therapy http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Tantitamit, Tanitra
U'wais, Ala
Huang, Kuan-Gen
An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title_full An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title_fullStr An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title_full_unstemmed An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title_short An Ultralate Female Growing Teratoma Syndrome: 19 Years after Aggressive Treatment for Advanced Ovarian Immature Teratoma
title_sort ultralate female growing teratoma syndrome: 19 years after aggressive treatment for advanced ovarian immature teratoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545050/
https://www.ncbi.nlm.nih.gov/pubmed/33101916
http://dx.doi.org/10.4103/GMIT.GMIT_70_18
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