Long-read sequencing for non-small-cell lung cancer genomes

Here, we report the application of a long-read sequencer, PromethION, for analyzing human cancer genomes. We first conducted whole-genome sequencing on lung cancer cell lines. We found that it is possible to genotype known cancerous mutations, such as point mutations. We also found that long-read se...

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Detalles Bibliográficos
Autores principales: Sakamoto, Yoshitaka, Xu, Liu, Seki, Masahide, Yokoyama, Toshiyuki T., Kasahara, Masahiro, Kashima, Yukie, Ohashi, Akihiro, Shimada, Yoko, Motoi, Noriko, Tsuchihara, Katsuya, Kobayashi, Susumu S., Kohno, Takashi, Shiraishi, Yuichi, Suzuki, Ayako, Suzuki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545141/
https://www.ncbi.nlm.nih.gov/pubmed/32887687
http://dx.doi.org/10.1101/gr.261941.120

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