Macrophage scavenger receptor 1 controls Chikungunya virus infection through autophagy in mice

Macrophage scavenger receptor 1 (MSR1) mediates the endocytosis of modified low-density lipoproteins and plays an important antiviral role. However, the molecular mechanism underlying MSR1 antiviral actions remains elusive. We report that MSR1 activates autophagy to restrict infection of Chikungunya...

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Detalles Bibliográficos
Autores principales: Yang, Long, Geng, Tingting, Yang, Guang, Ma, Jinzhu, Wang, Leilei, Ketkar, Harshada, Yang, Duomeng, Lin, Tao, Hwang, Jesse, Zhu, Shu, Wang, Yanlin, Dai, Jianfeng, You, Fuping, Cheng, Gong, Vella, Anthony T., Flavell, Richard. A., Fikrig, Erol, Wang, Penghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545163/
https://www.ncbi.nlm.nih.gov/pubmed/33033362
http://dx.doi.org/10.1038/s42003-020-01285-6

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