ZIF-8 as a promising drug delivery system for benznidazole: development, characterization, in vitro dialysis release and cytotoxicity

Chagas disease (CD), caused by the flagellate protozoan Trypanosoma cruzi, is one of the major public health problems in developing countries. Benznidazole (BNZ) is the only drug available for CD treatment in most countries, however, it presents high toxicity and low bioavailability. To address thes...

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Detalles Bibliográficos
Autores principales: de Moura Ferraz, Leslie Raphael, Tabosa, Alinne Élida Gonçalves Alves, da Silva Nascimento, Débora Dolores Souza, Ferreira, Aline Silva, de Albuquerque Wanderley Sales, Victor, Silva, José Yago Rodrigues, Júnior, Severino Alves, Rolim, Larissa Araújo, de Souza Pereira, Jorge José, Rolim-Neto, Pedro José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545170/
https://www.ncbi.nlm.nih.gov/pubmed/33033328
http://dx.doi.org/10.1038/s41598-020-73848-w

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