MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders

The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal...

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Detalles Bibliográficos
Autor principal: Smith, Moyra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545264/
https://www.ncbi.nlm.nih.gov/pubmed/33102526
http://dx.doi.org/10.3389/fmolb.2020.577710
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author Smith, Moyra
author_facet Smith, Moyra
author_sort Smith, Moyra
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description The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in neurodevelopmental, cognitive, and behavioral disorders.
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spelling pubmed-75452642020-10-22 MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders Smith, Moyra Front Mol Biosci Molecular Biosciences The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in neurodevelopmental, cognitive, and behavioral disorders. Frontiers Media S.A. 2020-09-25 /pmc/articles/PMC7545264/ /pubmed/33102526 http://dx.doi.org/10.3389/fmolb.2020.577710 Text en Copyright © 2020 Smith. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Smith, Moyra
MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_full MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_fullStr MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_full_unstemmed MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_short MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_sort mrna transcription, translation, and defects in developmental cognitive and behavioral disorders
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545264/
https://www.ncbi.nlm.nih.gov/pubmed/33102526
http://dx.doi.org/10.3389/fmolb.2020.577710
work_keys_str_mv AT smithmoyra mrnatranscriptiontranslationanddefectsindevelopmentalcognitiveandbehavioraldisorders

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