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The EB1–Kinesin-14 complex is required for efficient metaphase spindle assembly and kinetochore bi-orientation

Kinesin-14s are conserved molecular motors required for high-fidelity chromosome segregation, but their specific contributions to spindle function have not been fully defined. Here, we show that key functions of budding yeast Kinesin-14 Cik1-Kar3 are accomplished in a complex with Bim1 (yeast EB1)....

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Detalles Bibliográficos
Autores principales: Kornakov, Nikolay, Möllers, Bastian, Westermann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545359/
https://www.ncbi.nlm.nih.gov/pubmed/33044553
http://dx.doi.org/10.1083/jcb.202003072