Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing

BACKGROUND: The highly intra-tumoral heterogeneity and complex cell origination of prostate cancer greatly limits the utility of traditional bulk RNA sequencing in finding better biomarker for disease diagnosis and stratification. Tissue specimens based single-cell RNA sequencing holds great promise...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoshi, Guo, Jinan, Liu, Kaisheng, Chen, Lipeng, Liu, Dale, Dong, Shaowei, Xia, Jinquan, Long, Qiaoyun, Yue, Yongjian, Zhao, Pan, Hu, Fengyan, Xiao, Zhangang, Pan, Xinghua, Xiao, Kefeng, Cheng, Zhiqiang, Ke, Zunfu, Chen, Zhe-Sheng, Zou, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545561/
https://www.ncbi.nlm.nih.gov/pubmed/33032611
http://dx.doi.org/10.1186/s12943-020-01264-9

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