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Vedolizumab treatment across antiretroviral treatment interruption in chronic HIV infection: the HAVARTI protocol for a pilot dose-ranging clinical trial to assess safety, tolerance, immunological and virological activity
INTRODUCTION: Continuous antiretroviral therapy (ART) suppresses HIV plasma viral load (pVL) to very low levels, which allows for some immune recovery. Discontinuation of ART leads to pVL rebound from reservoirs of persistence and latency, and progressive immunodeficiency. One promising but controve...
Autores principales: | McGuinty, Michaeline, Angel, Jonathan B, Cooper, Curtis L, Cowan, Juthaporn, MacPherson, Paul A, Kumar, Ashok, Murthy, Sanjay, Sy, Richmond, Dennehy, Michelle, Tremblay, Nancy, Byrareddy, Siddappa N, Cameron, D William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545629/ https://www.ncbi.nlm.nih.gov/pubmed/33033101 http://dx.doi.org/10.1136/bmjopen-2020-041359 |
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