Cargando…

Landscape of FGF/FGFR Alterations in 12,372 Chinese Cancer Patients

Purpose: The aberrant of fibroblast growth factors and their receptors (FGF/FGFR) is an emerging target in the treatment of solid tumors. This study aimed to explore the landscape of FGF/FGFR alterations in a large cohort of cancer patients. Material and Methods: The formalin-fixed paraffin-embedded...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuo, Wei, He, Yan, Li, Wei, Wu, Hao, Zhao, Zhengyi, Zhang, Yuzi, Chen, Shiqing, Yin, Yongmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545692/ https://www.ncbi.nlm.nih.gov/pubmed/33046990 http://dx.doi.org/10.7150/jca.49269

Ejemplares similares

Molecular Landscape of ERBB2 Alterations in 14,956 Solid Tumors
por: Wang, Hao, et al.
Publicado: (2022)

Targeting the FGF/FGFR axis and its co-alteration allies
por: Uehara, Y., et al.
Publicado: (2022)

Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors
por: Jardim, Denis L F, et al.
Publicado: (2022)

Differential Specificity of Endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in Complex with KLB
por: Yang, Chaofeng, et al.
Publicado: (2012)

FGF/FGFR signaling in health and disease
por: Xie, Yangli, et al.
Publicado: (2020)

Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis
por: Zhang, Jinglin, et al.
Publicado: (2019)

Inhibition of FGF‐FGFR and VEGF‐VEGFR signalling in cancer treatment
por: Liu, Guihong, et al.
Publicado: (2021)

Expression of FGF8, FGF18, and FGFR4 in Gastroesophageal Adenocarcinomas
por: Jomrich, Gerd, et al.
Publicado: (2019)

LGG-20. LANDSCAPE OF FGFR ALTERATIONS IN PEDIATRIC AND AYA GLIOMAS
por: Nobre, Liana, et al.
Publicado: (2023)

FGF /FGFR Signal Induces Trachea Extension in the Drosophila Visual System
por: Chu, Wei-Chen, et al.
Publicado: (2013)

FGF19–FGFR4 Signaling in Hepatocellular Carcinoma
por: Raja, Aroosha, et al.
Publicado: (2019)

Chronic Voluntary Alcohol Consumption Alters Promoter Methylation and Expression of Fgf-2 and Fgfr1
por: Herburg, Leonie, et al.
Publicado: (2023)

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
por: Agrawal, Archita, et al.
Publicado: (2018)

FGF2 and FGFR2 in patients with idiopathic pulmonary fibrosis and lung cancer
por: Li, Li, et al.
Publicado: (2018)

Dual roles of endothelial FGF-2–FGFR1–PDGF-BB and perivascular FGF-2–FGFR2–PDGFRβ signaling pathways in tumor vascular remodeling
por: Hosaka, Kayoko, et al.
Publicado: (2018)

Mutant hFGF23(A12D) stimulates osteoblast differentiation through FGFR3
por: Tu, Yilin, et al.
Publicado: (2019)

Multi-organ FGF21-FGFR1 signaling in metabolic health and disease
por: Kaur, Namrita, et al.
Publicado: (2022)

Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment
por: Ruan, Ruiwen, et al.
Publicado: (2023)

Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23
por: Xiao, Zhousheng, et al.
Publicado: (2014)

A Network Map of FGF-1/FGFR Signaling System
por: Raju, Rajesh, et al.
Publicado: (2014)

The Emerging Role of the FGF/FGFR Pathway in Gastrointestinal Stromal Tumor
por: Astolfi, Annalisa, et al.
Publicado: (2020)

FGF/FGFR Pathways in Multiple Sclerosis and in Its Disease Models
por: Rajendran, Ranjithkumar, et al.
Publicado: (2021)

Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
por: Wiedlocha, Antoni, et al.
Publicado: (2021)

The role of TGF-β pathway alterations in immune regulation as a potential pan-cancer biomarker in immunotherapy
por: Liang, Yan, et al.
Publicado: (2021)

Landscape of IDH1/2 mutations in Chinese patients with solid tumors: A pan‐cancer analysis
por: Shen, Dong, et al.
Publicado: (2021)

MiR‐372‐3p promotes cell growth and metastasis by targeting FGF9 in lung squamous cell carcinoma
por: Wang, Qing, et al.
Publicado: (2017)

Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230
por: Blackwell, Christina, et al.
Publicado: (2016)

Expression Atlas of FGF and FGFR Genes in Pancancer Uncovered Predictive Biomarkers for Clinical Trials of Selective FGFR Inhibitors
por: Li, Yuan, et al.
Publicado: (2020)

THU372 Finasteride Induced Hyperglycemia
por: Bose, Vivek, et al.
Publicado: (2023)

VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway
por: Lee, Chunsik, et al.
Publicado: (2023)

FGF23/FGFR4-mediated left ventricular hypertrophy is reversible
por: Grabner, Alexander, et al.
Publicado: (2017)

The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives
por: Santolla, Maria Francesca, et al.
Publicado: (2020)

FGF/FGFR signaling pathway involved resistance in various cancer types
por: Zhou, Yangyang, et al.
Publicado: (2020)

Exploring the FGF/FGFR System in Ocular Tumors: New Insights and Perspectives
por: Loda, Alessandra, et al.
Publicado: (2022)

The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach
por: Rezzola, Sara, et al.
Publicado: (2019)

FGF2/FGFR1 regulates autophagy in FGFR1-amplified non-small cell lung cancer cells
por: Yuan, Hong, et al.
Publicado: (2017)

Inhibition of FGFR Signaling by Targeting FGF/FGFR Extracellular Interactions: Towards the Comprehension of the Molecular Mechanism through NMR Approaches
por: Pagano, Katiuscia, et al.
Publicado: (2022)

Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
por: Guo, Zhuojun, et al.
Publicado: (2022)

FGFR blockade inhibits targeted therapy-tolerant persister in basal FGFR1- and FGF2-high cancers with driver oncogenes
por: Furugaki, Koh, et al.
Publicado: (2023)

LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis
por: Xie, Tao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kfelle8v2l92l3o3quscfn482o