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Monocytes enhance the inflammatory response to TLR2 stimulation in aortic valve interstitial cells through paracrine up-regulation of TLR2 level
Background and Objectives: Chronic valvular inflammation associated with monocyte infiltration promotes calcific aortic valve disease (CAVD) progression. Further, innate immunity in aortic valve interstitial cells (AVICs), mediated by Toll-like receptors (TLRs), up-regulates cellular inflammatory, f...
Autores principales: | Zhang, Peijian, The, Erlinda, Nedumaran, Balachandar, Ao, Lihua, Jarrett, Michael J., Xu, Dingli, Fullerton, David A., Meng, Xianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545700/ https://www.ncbi.nlm.nih.gov/pubmed/33061818 http://dx.doi.org/10.7150/ijbs.49332 |
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