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Monocytes enhance the inflammatory response to TLR2 stimulation in aortic valve interstitial cells through paracrine up-regulation of TLR2 level

Background and Objectives: Chronic valvular inflammation associated with monocyte infiltration promotes calcific aortic valve disease (CAVD) progression. Further, innate immunity in aortic valve interstitial cells (AVICs), mediated by Toll-like receptors (TLRs), up-regulates cellular inflammatory, f...

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Detalles Bibliográficos
Autores principales: Zhang, Peijian, The, Erlinda, Nedumaran, Balachandar, Ao, Lihua, Jarrett, Michael J., Xu, Dingli, Fullerton, David A., Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545700/
https://www.ncbi.nlm.nih.gov/pubmed/33061818
http://dx.doi.org/10.7150/ijbs.49332

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