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Downregulation of MEG3 promotes neuroblastoma development through FOXO1-mediated autophagy and mTOR-mediated epithelial-mesenchymal transition

Our previous studies demonstrated that MEG3 was significantly downregulated in neuroblastoma (NB) and its expression was negatively associated with the INSS stage. Overexpression of MEG3 promoted apoptosis and inhibited proliferation in NB cells. In this study, we discovered more potential functions...

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Detalles Bibliográficos
Autores principales: Ye, Mujie, Lu, Hong, Tang, Weitao, Jing, Tianrui, Chen, Shiyu, Wei, Meng, Zhang, Jingjing, Wang, Jing, Ma, Jing, Ma, Duan, Dong, Kuiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545718/
https://www.ncbi.nlm.nih.gov/pubmed/33061817
http://dx.doi.org/10.7150/ijbs.48126