Peroxynitrite/PKR Axis Modulates the NLRP3 Inflammasome of Cardiac Fibroblasts

Sepsis/endotoxemia activates the NLRP3 inflammasome of macrophages leading to the maturation and release of IL-1β, an important mediator of the inflammatory response. Reactive oxygen species have been implicated in NLRP3 inflammasome activation. Further, our preliminary studies indicated that LPS ch...

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Detalles Bibliográficos
Autores principales: Lan, Ting, Tao, Aibin, Xu, Xuemei, Kvietys, Peter, Rui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545724/
https://www.ncbi.nlm.nih.gov/pubmed/33101273
http://dx.doi.org/10.3389/fimmu.2020.558712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545724/
https://www.ncbi.nlm.nih.gov/pubmed/33101273
http://dx.doi.org/10.3389/fimmu.2020.558712

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