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Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement

BACKGROUND AND PURPOSE: To assess the feasibility of a treatment planning system in localizing, contouring, and targeting lung lesions along with an evaluation of volume indices of lung involvement in patients with COVID-19 pneumonia. METHODS: We evaluated 10 patients with PCR-confirmed COVID-19 pne...

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Autores principales: Ghahramani-Asl, Ruhollah, Porouhan, Pejman, Mehrpouyan, Mohammad, Welsh, James S., Calabrese, Edward J., Kapoor, Rachna, Dhawan, Gaurav, Javadinia, Seyed Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545774/
https://www.ncbi.nlm.nih.gov/pubmed/33088245
http://dx.doi.org/10.1177/1559325820962600
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author Ghahramani-Asl, Ruhollah
Porouhan, Pejman
Mehrpouyan, Mohammad
Welsh, James S.
Calabrese, Edward J.
Kapoor, Rachna
Dhawan, Gaurav
Javadinia, Seyed Alireza
author_facet Ghahramani-Asl, Ruhollah
Porouhan, Pejman
Mehrpouyan, Mohammad
Welsh, James S.
Calabrese, Edward J.
Kapoor, Rachna
Dhawan, Gaurav
Javadinia, Seyed Alireza
author_sort Ghahramani-Asl, Ruhollah
collection PubMed
description BACKGROUND AND PURPOSE: To assess the feasibility of a treatment planning system in localizing, contouring, and targeting lung lesions along with an evaluation of volume indices of lung involvement in patients with COVID-19 pneumonia. METHODS: We evaluated 10 patients with PCR-confirmed COVID-19 pneumonia. The CT images were imported into the ISOgray® treatment planning system to anatomically define and contour the volumes of the pulmonary lesions, the lungs, and other nearby organs. RESULTS: The ratio of lung lesion volume to lung volume in this study was 0.11 ± 0.13 (11.13%). The highest mean biosynthesis ratio of lung lesions was 0.36. The ratio of lesion volume in the left lung of patients with the highest volume of involvement, was 0.44, and the ratio of lesion volume in the right lung of these patients was 0.27 (approximately 1.5 times more in the left lung than the right lung). On average, CTDIvol and DLP for all patients studied in our study were 11.22 ± 2.47 mGy and 354.20 ± 65.11 mGy.cm CONCLUSION: We reported the feasibility of using a treatment planning system in localizing COVID-19 pulmonary lesions and its validity in the volumetric assessment of infected lung regions.
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spelling pubmed-75457742020-10-20 Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement Ghahramani-Asl, Ruhollah Porouhan, Pejman Mehrpouyan, Mohammad Welsh, James S. Calabrese, Edward J. Kapoor, Rachna Dhawan, Gaurav Javadinia, Seyed Alireza Dose Response Original Article BACKGROUND AND PURPOSE: To assess the feasibility of a treatment planning system in localizing, contouring, and targeting lung lesions along with an evaluation of volume indices of lung involvement in patients with COVID-19 pneumonia. METHODS: We evaluated 10 patients with PCR-confirmed COVID-19 pneumonia. The CT images were imported into the ISOgray® treatment planning system to anatomically define and contour the volumes of the pulmonary lesions, the lungs, and other nearby organs. RESULTS: The ratio of lung lesion volume to lung volume in this study was 0.11 ± 0.13 (11.13%). The highest mean biosynthesis ratio of lung lesions was 0.36. The ratio of lesion volume in the left lung of patients with the highest volume of involvement, was 0.44, and the ratio of lesion volume in the right lung of these patients was 0.27 (approximately 1.5 times more in the left lung than the right lung). On average, CTDIvol and DLP for all patients studied in our study were 11.22 ± 2.47 mGy and 354.20 ± 65.11 mGy.cm CONCLUSION: We reported the feasibility of using a treatment planning system in localizing COVID-19 pulmonary lesions and its validity in the volumetric assessment of infected lung regions. SAGE Publications 2020-09-29 /pmc/articles/PMC7545774/ /pubmed/33088245 http://dx.doi.org/10.1177/1559325820962600 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Ghahramani-Asl, Ruhollah
Porouhan, Pejman
Mehrpouyan, Mohammad
Welsh, James S.
Calabrese, Edward J.
Kapoor, Rachna
Dhawan, Gaurav
Javadinia, Seyed Alireza
Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title_full Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title_fullStr Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title_full_unstemmed Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title_short Feasibility of Treatment Planning System in Localizing the COVID-19 Pneumonia Lesions and Evaluation of Volume Indices of Lung Involvement
title_sort feasibility of treatment planning system in localizing the covid-19 pneumonia lesions and evaluation of volume indices of lung involvement
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545774/
https://www.ncbi.nlm.nih.gov/pubmed/33088245
http://dx.doi.org/10.1177/1559325820962600
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