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Functional polymorphisms and transcriptional analysis in the 5′ region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders

BACKGROUND: The 5-hydroxytryptamine 1B receptor (5-HT1B) plays an essential role in the serotonin (5-HT) system and is widely involved in a variety of brain activities. HTR1B is the gene encoding 5-HT1B. Genome-wide association studies have shown that HTR1B polymorphisms are closely related to multi...

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Detalles Bibliográficos
Autores principales: Xia, Xi, Ding, Mei, Xuan, Jin-feng, Xing, Jia-xin, Yao, Jun, Wu, Xue, Wang, Bao-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545834/
https://www.ncbi.nlm.nih.gov/pubmed/33036580
http://dx.doi.org/10.1186/s12888-020-02906-4