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The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial
BACKGROUND: New approaches on paediatric cancer treatment aim to maintain long-term health. As a result of radiotherapy, chemotherapy or surgery, paediatric cancer survivors tend to suffer from any chronic health condition. Endocrine dysfunction represents one of the most common issues and affects b...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545891/ https://www.ncbi.nlm.nih.gov/pubmed/33032564 http://dx.doi.org/10.1186/s12889-020-09607-3 |
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author | Gil-Cosano, Jose J. Ubago-Guisado, Esther Sánchez, Maria J. Ortega-Acosta, Maria J. Mateos, Maria E. Benito-Bernal, Ana I. Llorente-Cantarero, Francisco J. Ortega, Francisco B. Ruiz, Jonatan R. Labayen, Idoia Martinez-Vizcaino, Vicente Vlachopoulos, Dimitris Arroyo-Morales, Manuel Muñoz-Torres, Manuel Pascual-Gázquez, Juan F. Vicho-González, Maria C. Gracia-Marco, Luis |
author_facet | Gil-Cosano, Jose J. Ubago-Guisado, Esther Sánchez, Maria J. Ortega-Acosta, Maria J. Mateos, Maria E. Benito-Bernal, Ana I. Llorente-Cantarero, Francisco J. Ortega, Francisco B. Ruiz, Jonatan R. Labayen, Idoia Martinez-Vizcaino, Vicente Vlachopoulos, Dimitris Arroyo-Morales, Manuel Muñoz-Torres, Manuel Pascual-Gázquez, Juan F. Vicho-González, Maria C. Gracia-Marco, Luis |
author_sort | Gil-Cosano, Jose J. |
collection | PubMed |
description | BACKGROUND: New approaches on paediatric cancer treatment aim to maintain long-term health. As a result of radiotherapy, chemotherapy or surgery, paediatric cancer survivors tend to suffer from any chronic health condition. Endocrine dysfunction represents one of the most common issues and affects bone health. Exercise is key for bone mass accrual during growth, specifically plyometric jump training. The iBoneFIT study will investigate the effect of a 9-month online exercise programme on bone health in paediatric cancer survivors. This study will also examine the effect of the intervention on body composition, physical fitness, physical activity, calcium intake, vitamin D, blood samples quality of life and mental health. METHODS: A minimum of 116 participants aged 6 to 18 years will be randomized into an intervention (n = 58) or control group (n = 58). The intervention group will receive an online exercise programme and diet counselling on calcium and vitamin D. In addition, five behaviour change techniques and a gamification design will be implemented in order to increase the interest of this non-game programme. The control group will only receive diet counselling. Participants will be assessed on 3 occasions: 1) at baseline; 2) after the 9 months of the intervention; 3) 4 months following the intervention. The primary outcome will be determined by dual energy X-ray absorptiometry (DXA) and the hip structural analysis, trabecular bone score and 3D-DXA softwares. Secondary outcomes will include anthropometry, body composition, physical fitness, physical activity, calcium and vitamin D intake, blood samples, quality of life and mental health. DISCUSSION: Whether a simple, feasible and short in duration exercise programme can improve bone health has not been examined in paediatric cancer survivors. This article describes the design, rationale and methods of a study intended to test the effect of a rigorous online exercise programme on bone health in paediatric cancer survivors. If successful, the iBoneFIT study will contribute to decrease chronic health conditions in this population and will have a positive impact in the society. TRIAL REGISTRATION: Prospectively registered in isrctn.com: isrctn61195625. Registered 2 April 2020. |
format | Online Article Text |
id | pubmed-7545891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-75458912020-10-13 The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial Gil-Cosano, Jose J. Ubago-Guisado, Esther Sánchez, Maria J. Ortega-Acosta, Maria J. Mateos, Maria E. Benito-Bernal, Ana I. Llorente-Cantarero, Francisco J. Ortega, Francisco B. Ruiz, Jonatan R. Labayen, Idoia Martinez-Vizcaino, Vicente Vlachopoulos, Dimitris Arroyo-Morales, Manuel Muñoz-Torres, Manuel Pascual-Gázquez, Juan F. Vicho-González, Maria C. Gracia-Marco, Luis BMC Public Health Study Protocol BACKGROUND: New approaches on paediatric cancer treatment aim to maintain long-term health. As a result of radiotherapy, chemotherapy or surgery, paediatric cancer survivors tend to suffer from any chronic health condition. Endocrine dysfunction represents one of the most common issues and affects bone health. Exercise is key for bone mass accrual during growth, specifically plyometric jump training. The iBoneFIT study will investigate the effect of a 9-month online exercise programme on bone health in paediatric cancer survivors. This study will also examine the effect of the intervention on body composition, physical fitness, physical activity, calcium intake, vitamin D, blood samples quality of life and mental health. METHODS: A minimum of 116 participants aged 6 to 18 years will be randomized into an intervention (n = 58) or control group (n = 58). The intervention group will receive an online exercise programme and diet counselling on calcium and vitamin D. In addition, five behaviour change techniques and a gamification design will be implemented in order to increase the interest of this non-game programme. The control group will only receive diet counselling. Participants will be assessed on 3 occasions: 1) at baseline; 2) after the 9 months of the intervention; 3) 4 months following the intervention. The primary outcome will be determined by dual energy X-ray absorptiometry (DXA) and the hip structural analysis, trabecular bone score and 3D-DXA softwares. Secondary outcomes will include anthropometry, body composition, physical fitness, physical activity, calcium and vitamin D intake, blood samples, quality of life and mental health. DISCUSSION: Whether a simple, feasible and short in duration exercise programme can improve bone health has not been examined in paediatric cancer survivors. This article describes the design, rationale and methods of a study intended to test the effect of a rigorous online exercise programme on bone health in paediatric cancer survivors. If successful, the iBoneFIT study will contribute to decrease chronic health conditions in this population and will have a positive impact in the society. TRIAL REGISTRATION: Prospectively registered in isrctn.com: isrctn61195625. Registered 2 April 2020. BioMed Central 2020-10-08 /pmc/articles/PMC7545891/ /pubmed/33032564 http://dx.doi.org/10.1186/s12889-020-09607-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Study Protocol Gil-Cosano, Jose J. Ubago-Guisado, Esther Sánchez, Maria J. Ortega-Acosta, Maria J. Mateos, Maria E. Benito-Bernal, Ana I. Llorente-Cantarero, Francisco J. Ortega, Francisco B. Ruiz, Jonatan R. Labayen, Idoia Martinez-Vizcaino, Vicente Vlachopoulos, Dimitris Arroyo-Morales, Manuel Muñoz-Torres, Manuel Pascual-Gázquez, Juan F. Vicho-González, Maria C. Gracia-Marco, Luis The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title | The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title_full | The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title_fullStr | The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title_full_unstemmed | The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title_short | The effect of an online exercise programme on bone health in paediatric cancer survivors (iBoneFIT): study protocol of a multi-centre randomized controlled trial |
title_sort | effect of an online exercise programme on bone health in paediatric cancer survivors (ibonefit): study protocol of a multi-centre randomized controlled trial |
topic | Study Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545891/ https://www.ncbi.nlm.nih.gov/pubmed/33032564 http://dx.doi.org/10.1186/s12889-020-09607-3 |
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