Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma

BACKGROUND: Toll-like receptor 3 (TLR3) ligand which activates TLR3 signaling induces both cancer cell death and activates anti-tumor immunity. However, TLR3 signaling can also harbor pro-tumorigenic consequences. Therefore, we examined the status of TLR3 in cholangiocarcinoma (CCA) cases to better...

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Detalles Bibliográficos
Autores principales: Lomphithak, Thanpisit, Choksi, Swati, Mutirangura, Apiwat, Tohtong, Rutaiwan, Tencomnao, Tewin, Usubuchi, Hajime, Unno, Michiaki, Sasano, Hironobu, Jitkaew, Siriporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545934/
https://www.ncbi.nlm.nih.gov/pubmed/33036630
http://dx.doi.org/10.1186/s12964-020-00661-3

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