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Extracellular vesicles derived from Krüppel-Like Factor 2-overexpressing endothelial cells attenuate myocardial ischemia-reperfusion injury by preventing Ly6C(high) monocyte recruitment
Background: The ischemia/reperfusion (I/R) process in patients with ST-segment elevation myocardial infarction (STEMI) triggers an immune response, resulting in myocyte death. Krüppel-Like Factor 2 (KLF2), which is highly expressed in endothelial cells (ECs) under laminar flow, exerts anti-inflammat...
Autores principales: | Qiao, Shuaihua, Zhang, Wenfeng, Yin, Yong, Wei, Zhonghai, Chen, Fu, Zhao, Jinxuan, Sun, Xuan, Mu, Dan, Xie, Jun, Xu, Biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545985/ https://www.ncbi.nlm.nih.gov/pubmed/33052233 http://dx.doi.org/10.7150/thno.45459 |
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