Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-κB signaling axis in lung cancer cells and denotes a therapeutic opportunity

Purpose: Clinical success of precision medicine is severely limited by de novo or acquired drug resistance. It remains a clinically unmet need to treat these patients. Tumor suppressor genes (TSGs) play a critical role in tumorigenesis and impact the therapeutic effect of various treatments. Experim...

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Detalles Bibliográficos
Autores principales: Chen, Zhipeng, Fan, Zhenzhen, Dou, Xiaowei, Zhou, Qian, Zeng, Guandi, Liu, Lu, Chen, Wensheng, Lan, Ruirui, Liu, Wanting, Ru, Guoqing, Yu, Lei, He, Qing-Yu, Chen, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545994/
https://www.ncbi.nlm.nih.gov/pubmed/33052230
http://dx.doi.org/10.7150/thno.44829

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