Cargando…

FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma

Objective: The transcription factor forkhead box protein O1 (FOXO1) is critical for regulating cytokine and chemokine secretion. However, its function in the tumor microenvironment (TME) remains largely unexplored. In this study, we characterized the prognostic value of FOXO1 and the interaction bet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ying, Lyu, Zhaojie, Qin, Yanru, Wang, Xia, Sun, Liangzhan, Zhang, Yu, Gong, Lanqi, Wu, Shayi, Han, Shuo, Tang, Ying, Jia, Yongxu, Kwong, Dora Lai-Wan, Kam, NgarWoon, Guan, Xin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546008/ https://www.ncbi.nlm.nih.gov/pubmed/33052231 http://dx.doi.org/10.7150/thno.45261

Ejemplares similares

Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma
por: Kam, Ngar Woon, et al.
Publicado: (2021)

Single‐Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma
por: Jia, Yongxu, et al.
Publicado: (2023)

Functions of double‐negative B cells in autoimmune diseases, infections, and cancers
por: Chung, Michael King Yung, et al.
Publicado: (2023)

Predictive significance of HMGCS2 for prognosis in resected Chinese esophageal squamous cell carcinoma patients
por: Tang, Hong, et al.
Publicado: (2017)

Correction: C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
por: Zhang, Yu, et al.
Publicado: (2021)

C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
por: Zhang, Yu, et al.
Publicado: (2020)

miR-21 Overexpression Promotes Esophageal Squamous Cell Carcinoma Invasion and Migration by Repressing Tropomyosin 1
por: Shen, Zhuojian, et al.
Publicado: (2020)

Ferroptosis patterns and tumor microenvironment infiltration characterization in esophageal squamous cell cancer
por: Zhang, Lu-Lu, et al.
Publicado: (2022)

RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression
por: Ming, Xiao-Yan, et al.
Publicado: (2018)

MAEL Augments Cancer Stemness Properties and Resistance to Sorafenib in Hepatocellular Carcinoma through the PTGS2/AKT/STAT3 Axis
por: Shi, Chaoran, et al.
Publicado: (2022)

Ablation of MCM10 using CRISPR/Cas9 restrains the growth and migration of esophageal squamous cell carcinoma cells through inhibition of Akt signaling
por: Yan, Jie, et al.
Publicado: (2018)

Esophageal Squamous Cell Carcinoma with Marked Eosinophil Infiltration
por: Fukuchi, Minoru, et al.
Publicado: (2011)

An inflammation-related nomogram for predicting the survival of patients with non-small cell lung cancer after pulmonary lobectomy
por: Wang, Ying, et al.
Publicado: (2018)

Characterization of the Immune Cell Infiltration Landscape in Esophageal Squamous Cell Carcinoma
por: Sui, Zhilin, et al.
Publicado: (2022)

Histological Regression of Squamous Esophageal Carcinoma Assessed by Percentage of Residual Viable Cells after Neoadjuvant Chemoradiation is an Important Prognostic Factor
por: Tong, Daniel King Hung, et al.
Publicado: (2010)

PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors
por: Yan, Qian, et al.
Publicado: (2021)

Tumor budding and tumor‐infiltrating lymphocytes can predict prognosis in pT1b esophageal squamous cell carcinoma
por: Li, Zhuo, et al.
Publicado: (2023)

Reduction of AZGP1 predicts poor prognosis in esophageal squamous cell carcinoma patients in Northern China
por: Tang, Hong, et al.
Publicado: (2016)

Phenotypic profiling and prognostic significance of immune infiltrates in esophageal squamous cell carcinoma
por: Pan, Chuqing, et al.
Publicado: (2021)

Clinical efficacy and survival analysis of apatinib combined with docetaxel in advanced esophageal cancer
por: Li, Jing, et al.
Publicado: (2019)

The Functionalities and Clinical Significance of Tumor-Infiltrating Immune Cells in Esophageal Squamous Cell Carcinoma
por: Zhang, Jishuai, et al.
Publicado: (2021)

Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer
por: Zhaojie, Lyu, et al.
Publicado: (2019)

Tumour infiltrating lymphocytes correlate with improved survival in patients with esophageal squamous cell carcinoma
por: Jiang, Dongxian, et al.
Publicado: (2017)

Prognostic Value of Tumor-Infiltrating Lymphocytes Differs Depending on Lymphocyte Subsets in Esophageal Squamous Cell Carcinoma: An Updated Meta-Analysis
por: Hao, Jiatao, et al.
Publicado: (2020)

Characterization of Tumor Suppressive Function of cornulin in Esophageal Squamous Cell Carcinoma
por: Chen, Kai, et al.
Publicado: (2013)

The Stromal and Immune Landscape of Nasopharyngeal Carcinoma and Its Implications for Precision Medicine Targeting the Tumor Microenvironment
por: Gong, Lanqi, et al.
Publicado: (2021)

Genome-Wide Gene Expression Profile Analyses Identify CTTN as a Potential Prognostic Marker in Esophageal Cancer
por: Lu, Pei, et al.
Publicado: (2014)

Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)
por: Lu, Yi-fang, et al.
Publicado: (2018)

A Case of Esophageal Squamous Papillomatosis
por: Park, Sang-Hyun, et al.
Publicado: (2012)

Machine Learning and Novel Biomarkers Associated with Immune Infiltration for the Diagnosis of Esophageal Squamous Cell Carcinoma
por: Zhang, Jipeng, et al.
Publicado: (2022)

Increased miRNA-22 expression sensitizes esophageal squamous cell carcinoma to irradiation
por: Wang, Xiao-chun, et al.
Publicado: (2013)

Tumor-Infiltrating CD4+ Lymphocytes Predict a Favorable Survival in Patients with Operable Esophageal Squamous Cell Carcinoma
por: Chen, Kaiyan, et al.
Publicado: (2017)

CD103(+) tumor-infiltrating lymphocytes predict favorable prognosis in patients with esophageal squamous cell carcinoma
por: Chu, Yifan, et al.
Publicado: (2019)

Expression of 4-hydroxynonenal in esophageal squamous cell carcinoma
por: Zhang, Ying, et al.
Publicado: (2017)

Immune Infiltration Represents Potential Diagnostic and Prognostic Biomarkers for Esophageal Squamous Cell Carcinoma
por: Li, Mengxiang, et al.
Publicado: (2022)

Correction to: Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)
por: Lu, Yi-fang, et al.
Publicado: (2020)

Identification of prognostic genes and tumor-infiltrating immune cells in the tumor microenvironment of esophageal squamous cell carcinoma and esophageal adenocarcinoma
por: Huai, Qilin, et al.
Publicado: (2021)

Profiles of immune cell infiltration and immune-related genes in the tumor microenvironment of esophageal squamous cell carcinoma
por: Liu, Mingdi, et al.
Publicado: (2021)

Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5
por: Chang, Zhiwei, et al.
Publicado: (2021)

The Accumulation and Prognosis Value of Tumor Infiltrating IL-17 Producing Cells in Esophageal Squamous Cell Carcinoma
por: Lv, Lin, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_ompa0jed8r8gkjqp8g435l937a