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Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital fr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546073/ https://www.ncbi.nlm.nih.gov/pubmed/33100750 http://dx.doi.org/10.4103/UA.UA_62_19 |
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author | Agwu, Ngwobia Peter Muhammad, Abubakar Sadiq Abdullahi, Abdulwahab-Ahmed Bashir, Bello Legbo, Jacob Ndas Mungadi, Ismaila Arzika |
author_facet | Agwu, Ngwobia Peter Muhammad, Abubakar Sadiq Abdullahi, Abdulwahab-Ahmed Bashir, Bello Legbo, Jacob Ndas Mungadi, Ismaila Arzika |
author_sort | Agwu, Ngwobia Peter |
collection | PubMed |
description | INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital from January 2001 to June 2017. Data were entered into a semi-structured pro forma and analyzed using SPSS version 20.0. RESULTS: The mean age of the patients was 42.7 ± 19.4 years, with age range of 7 weeks to 72 years. All the patients were male. The patients had underlying urologic conditions in 27.6%, 15.0% were postoperative, 4.2% had anorectal diseases, 10.6% had medical conditions, and 42.6% were idiopathic. After resuscitation, all the patients had serial debridement, Hypertonic saline bath, broad spectrum antibiotics and wound dressing. The wound healed by secondary intention in 34.0% and 32.3% of the patients had wound closure ± skin graft. The treatment was successful in 68.0% of the patients, 15.0% left against medical advice, and 17.0% died of severe sepsis. CONCLUSION: FG mainly affects men with existing urologic conditions in our environment. Aggressive debridement, hypertonic saline sitz bath, broad-spectrum antibiotics, and appropriate wound care are associated with good outcome. |
format | Online Article Text |
id | pubmed-7546073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-75460732020-10-22 Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting Agwu, Ngwobia Peter Muhammad, Abubakar Sadiq Abdullahi, Abdulwahab-Ahmed Bashir, Bello Legbo, Jacob Ndas Mungadi, Ismaila Arzika Urol Ann Original Article INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital from January 2001 to June 2017. Data were entered into a semi-structured pro forma and analyzed using SPSS version 20.0. RESULTS: The mean age of the patients was 42.7 ± 19.4 years, with age range of 7 weeks to 72 years. All the patients were male. The patients had underlying urologic conditions in 27.6%, 15.0% were postoperative, 4.2% had anorectal diseases, 10.6% had medical conditions, and 42.6% were idiopathic. After resuscitation, all the patients had serial debridement, Hypertonic saline bath, broad spectrum antibiotics and wound dressing. The wound healed by secondary intention in 34.0% and 32.3% of the patients had wound closure ± skin graft. The treatment was successful in 68.0% of the patients, 15.0% left against medical advice, and 17.0% died of severe sepsis. CONCLUSION: FG mainly affects men with existing urologic conditions in our environment. Aggressive debridement, hypertonic saline sitz bath, broad-spectrum antibiotics, and appropriate wound care are associated with good outcome. Wolters Kluwer - Medknow 2020 2020-07-17 /pmc/articles/PMC7546073/ /pubmed/33100750 http://dx.doi.org/10.4103/UA.UA_62_19 Text en Copyright: © 2020 Urology Annals http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Agwu, Ngwobia Peter Muhammad, Abubakar Sadiq Abdullahi, Abdulwahab-Ahmed Bashir, Bello Legbo, Jacob Ndas Mungadi, Ismaila Arzika Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title | Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title_full | Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title_fullStr | Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title_full_unstemmed | Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title_short | Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting |
title_sort | pattern and outcome of management of fournier's gangrene in a resource-constraint setting |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546073/ https://www.ncbi.nlm.nih.gov/pubmed/33100750 http://dx.doi.org/10.4103/UA.UA_62_19 |
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