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Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting

INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital fr...

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Autores principales: Agwu, Ngwobia Peter, Muhammad, Abubakar Sadiq, Abdullahi, Abdulwahab-Ahmed, Bashir, Bello, Legbo, Jacob Ndas, Mungadi, Ismaila Arzika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546073/
https://www.ncbi.nlm.nih.gov/pubmed/33100750
http://dx.doi.org/10.4103/UA.UA_62_19
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author Agwu, Ngwobia Peter
Muhammad, Abubakar Sadiq
Abdullahi, Abdulwahab-Ahmed
Bashir, Bello
Legbo, Jacob Ndas
Mungadi, Ismaila Arzika
author_facet Agwu, Ngwobia Peter
Muhammad, Abubakar Sadiq
Abdullahi, Abdulwahab-Ahmed
Bashir, Bello
Legbo, Jacob Ndas
Mungadi, Ismaila Arzika
author_sort Agwu, Ngwobia Peter
collection PubMed
description INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital from January 2001 to June 2017. Data were entered into a semi-structured pro forma and analyzed using SPSS version 20.0. RESULTS: The mean age of the patients was 42.7 ± 19.4 years, with age range of 7 weeks to 72 years. All the patients were male. The patients had underlying urologic conditions in 27.6%, 15.0% were postoperative, 4.2% had anorectal diseases, 10.6% had medical conditions, and 42.6% were idiopathic. After resuscitation, all the patients had serial debridement, Hypertonic saline bath, broad spectrum antibiotics and wound dressing. The wound healed by secondary intention in 34.0% and 32.3% of the patients had wound closure ± skin graft. The treatment was successful in 68.0% of the patients, 15.0% left against medical advice, and 17.0% died of severe sepsis. CONCLUSION: FG mainly affects men with existing urologic conditions in our environment. Aggressive debridement, hypertonic saline sitz bath, broad-spectrum antibiotics, and appropriate wound care are associated with good outcome.
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spelling pubmed-75460732020-10-22 Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting Agwu, Ngwobia Peter Muhammad, Abubakar Sadiq Abdullahi, Abdulwahab-Ahmed Bashir, Bello Legbo, Jacob Ndas Mungadi, Ismaila Arzika Urol Ann Original Article INTRODUCTION: Fournier's gangrene (FG) is a necrotizing fasciitis of the external genitalia and perineum but may involve upper thigh and anterior abdominal wall. PATIENTS AND METHODS: This is a retrospective study of 47 patients managed for FG at Usmanu Danfodiyo University Teaching Hospital from January 2001 to June 2017. Data were entered into a semi-structured pro forma and analyzed using SPSS version 20.0. RESULTS: The mean age of the patients was 42.7 ± 19.4 years, with age range of 7 weeks to 72 years. All the patients were male. The patients had underlying urologic conditions in 27.6%, 15.0% were postoperative, 4.2% had anorectal diseases, 10.6% had medical conditions, and 42.6% were idiopathic. After resuscitation, all the patients had serial debridement, Hypertonic saline bath, broad spectrum antibiotics and wound dressing. The wound healed by secondary intention in 34.0% and 32.3% of the patients had wound closure ± skin graft. The treatment was successful in 68.0% of the patients, 15.0% left against medical advice, and 17.0% died of severe sepsis. CONCLUSION: FG mainly affects men with existing urologic conditions in our environment. Aggressive debridement, hypertonic saline sitz bath, broad-spectrum antibiotics, and appropriate wound care are associated with good outcome. Wolters Kluwer - Medknow 2020 2020-07-17 /pmc/articles/PMC7546073/ /pubmed/33100750 http://dx.doi.org/10.4103/UA.UA_62_19 Text en Copyright: © 2020 Urology Annals http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Agwu, Ngwobia Peter
Muhammad, Abubakar Sadiq
Abdullahi, Abdulwahab-Ahmed
Bashir, Bello
Legbo, Jacob Ndas
Mungadi, Ismaila Arzika
Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title_full Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title_fullStr Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title_full_unstemmed Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title_short Pattern and outcome of management of Fournier's gangrene in a resource-constraint setting
title_sort pattern and outcome of management of fournier's gangrene in a resource-constraint setting
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546073/
https://www.ncbi.nlm.nih.gov/pubmed/33100750
http://dx.doi.org/10.4103/UA.UA_62_19
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