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A Kunitz-type peptide from Dendroaspis polylepis venom as a simultaneous inhibitor of serine and cysteine proteases

BACKGROUND: Proteases play an important role for the proper physiological functions of the most diverse organisms. When unregulated, they are associated with several pathologies. Therefore, proteases have become potential therapeutic targets regarding the search for inhibitors. Snake venoms are comp...

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Detalles Bibliográficos
Autores principales: Kodama, Roberto Tadashi, Kuniyoshi, Alexandre Kazuo, da Silva, Cristiane Castilho Fernandes, Cajado-Carvalho, Daniela, Duzzi, Bruno, Mariano, Douglas Ceolin, Pimenta, Daniel C., Borges, Rafael, da Silva, Wilmar Dias, Portaro, Fernanda Calheta Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546081/
https://www.ncbi.nlm.nih.gov/pubmed/33088285
http://dx.doi.org/10.1590/1678-9199-JVATITD-2020-0037