Cargando…
Expression of TAM-R in Human Immune Cells and Unique Regulatory Function of MerTK in IL-10 Production by Tolerogenic DC
Tumor-infiltrating myeloid cells are a key component of the immune infiltrate often correlated with a poor prognosis due to their capacities to sustain an immunosuppressive environment. Among membrane receptors implicated in myeloid cell functions, Tyro3, Axl, and MerTK, which are a family of tyrosi...
Autores principales: | Giroud, Paul, Renaudineau, Sarah, Gudefin, Laura, Calcei, Alexandre, Menguy, Thierry, Rozan, Caroline, Mizrahi, Jacques, Caux, Christophe, Duong, Vanessa, Valladeau-Guilemond, Jenny |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546251/ https://www.ncbi.nlm.nih.gov/pubmed/33101282 http://dx.doi.org/10.3389/fimmu.2020.564133 |
Ejemplares similares
-
MerTK inhibition by RXDX-106 in MerTK activated gastric cancer cell lines
por: Kim, Jung Eun, et al.
Publicado: (2017) -
Targeting Tyro3, Axl and MerTK (TAM receptors): implications for macrophages in the tumor microenvironment
por: Myers, Kayla V., et al.
Publicado: (2019) -
Harnessing MerTK agonism for targeted therapeutics
por: Kedage, Vivekananda, et al.
Publicado: (2019) -
Dual targeting of TAM receptors Tyro3, Axl, and MerTK: Role in tumors and the tumor immune microenvironment
por: Wang, Kai-Hung, et al.
Publicado: (2020) -
MerTK, a risk factor for NASH fibrosis
por: Wang, Xiaobo, et al.
Publicado: (2020)