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Nuclear Transport Deficits in Tau-Related Neurodegenerative Diseases

Tau is a cytosolic microtubule binding protein that is highly abundant in the axons of the central nervous system. However, alternative functions of tau also in other cellular compartments are suggested, for example, in the nucleus, where interactions of tau with specific nuclear entities such as DN...

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Detalles Bibliográficos
Autores principales: Diez, Lisa, Wegmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546323/
https://www.ncbi.nlm.nih.gov/pubmed/33101165
http://dx.doi.org/10.3389/fneur.2020.01056