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Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism

Matrine (MAT), a quinolizidine alkaloid component derived from the root of Sophora flavescens, suppresses experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), by inducing the production of immunomodulatory molecules, e.g., IL-10. In an effort to find the upst...

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Detalles Bibliográficos
Autores principales:	Chu, Yao-Juan, Ma, Wen-Di, Thome, Rodolfo, Ping, Jie-Dan, Liu, Fang-Zhou, Wang, Meng-Ru, Zhang, Ming-Liang, Zhang, Guangxian, Zhu, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546369/ https://www.ncbi.nlm.nih.gov/pubmed/33101289 http://dx.doi.org/10.3389/fimmu.2020.569530

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