Interleukin-13 Alters Tight Junction Proteins Expression Thereby Compromising Barrier Function and Dampens Rhinovirus Induced Immune Responses in Nasal Epithelium

Tight junctions (TJs) are intercellular structures which are essential for epithelial barrier function and play an important role in antimicrobial defense. Epithelium dysfunction and type-2-skewed inflammation are two main pathological phenomena of chronic rhinosinusitis with nasal polyps (CRSwNP)....

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Detalles Bibliográficos
Autores principales: Huang, Zhi-Qun, Liu, Jing, Ong, Hsiao Hui, Yuan, Tian, Zhou, Xiang-Min, Wang, Jun, Tan, Kai Sen, Chow, Vincent T., Yang, Qin-Tai, Shi, Li, Ye, Jing, Wang, De-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546404/
https://www.ncbi.nlm.nih.gov/pubmed/33102478
http://dx.doi.org/10.3389/fcell.2020.572749

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