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A novel assay for drug screening that utilizes the heat shock response of Caenorhabditis elegans nematodes

Biological organisms respond to environmental stressors by recruiting multiple cellular cascades that act to mitigate damage and ultimately enhance survival. This implies that compounds that interact with any of those pathways might improve organism's survival. Here, we report on an initial att...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Hsiung, Patel, Rahul, Bortolami, Alessandro, Sesti, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546469/
https://www.ncbi.nlm.nih.gov/pubmed/33035268
http://dx.doi.org/10.1371/journal.pone.0240255