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A novel assay for drug screening that utilizes the heat shock response of Caenorhabditis elegans nematodes
Biological organisms respond to environmental stressors by recruiting multiple cellular cascades that act to mitigate damage and ultimately enhance survival. This implies that compounds that interact with any of those pathways might improve organism's survival. Here, we report on an initial att...
Autores principales: | Chen, Chih-Hsiung, Patel, Rahul, Bortolami, Alessandro, Sesti, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546469/ https://www.ncbi.nlm.nih.gov/pubmed/33035268 http://dx.doi.org/10.1371/journal.pone.0240255 |
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