NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation

The transcription factor nuclear factor I-A (NFIA) is a regulator of brown adipocyte differentiation. Here we show that the C-terminal 17 amino acid residues of NFIA (which we call pro#3 domain) are required for the transcriptional activity of NFIA. Full-length NFIA—but not deletion mutant lacking p...

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Detalles Bibliográficos
Autores principales: Hiraike, Yuta, Waki, Hironori, Miyake, Kana, Wada, Takahito, Oguchi, Misato, Saito, Kaede, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Yamauchi, Toshimasa, Kadowaki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546476/
https://www.ncbi.nlm.nih.gov/pubmed/32991581
http://dx.doi.org/10.1371/journal.pgen.1009044

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