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Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells

The two T-box transcription factors T-bet and Eomesodermin (Eomes) are important regulators of cytotoxic lymphocytes (CTLs), such as activated CD8 T cells, which are essential in the fight against intracellular pathogens and tumors. Both transcription factors share a great degree of homology based o...

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Detalles Bibliográficos
Autores principales:	Fixemer, Jonas, Hummel, Jonas F., Arnold, Frederic, Klose, Christoph S. N., Hofherr, Alexis, Weissert, Kristoffer, Kögl, Tamara, Köttgen, Michael, Arnold, Sebastian J., Aichele, Peter, Tanriver, Yakup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546498/ https://www.ncbi.nlm.nih.gov/pubmed/32991634 http://dx.doi.org/10.1371/journal.ppat.1008870

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