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Two-step mixed model approach to analyzing differential alternative RNA splicing

Changes in gene expression can correlate with poor disease outcomes in two ways: through changes in relative transcript levels or through alternative RNA splicing leading to changes in relative abundance of individual transcript isoforms. The objective of this research is to develop new statistical...

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Detalles Bibliográficos
Autores principales: Luo, Li, Kang, Huining, Li, Xichen, Ness, Scott A., Stidley, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546511/
https://www.ncbi.nlm.nih.gov/pubmed/33035235
http://dx.doi.org/10.1371/journal.pone.0232646

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