Cargando…
Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease
Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of posto...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546597/ https://www.ncbi.nlm.nih.gov/pubmed/33052294 http://dx.doi.org/10.7759/cureus.10333 |
_version_ | 1783592250714882048 |
---|---|
author | Hayat, Muhammad Hashim Moazzam, Zorays Ziogas, Ioannis A Yousaf, Amman Hayat, Maham |
author_facet | Hayat, Muhammad Hashim Moazzam, Zorays Ziogas, Ioannis A Yousaf, Amman Hayat, Maham |
author_sort | Hayat, Muhammad Hashim |
collection | PubMed |
description | Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of postoperative complications and re-transplantation in this group. We present the disease course, management, and outcome of a patient with Graves’ disease who presented with ALF secondary to thyroid storm. Thyrotoxicosis should always be included in the differential diagnosis of ALF, as timely diagnosis and management are crucial in achieving survival. |
format | Online Article Text |
id | pubmed-7546597 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-75465972020-10-12 Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease Hayat, Muhammad Hashim Moazzam, Zorays Ziogas, Ioannis A Yousaf, Amman Hayat, Maham Cureus Endocrinology/Diabetes/Metabolism Although mild elevations in liver enzymes are relatively common in thyrotoxicosis, acute liver failure (ALF) is an infrequent occurrence. Despite the emergence of liver transplantation as a viable treatment for ALF, survival rates continue to remain unsatisfactory, coupled with higher rates of postoperative complications and re-transplantation in this group. We present the disease course, management, and outcome of a patient with Graves’ disease who presented with ALF secondary to thyroid storm. Thyrotoxicosis should always be included in the differential diagnosis of ALF, as timely diagnosis and management are crucial in achieving survival. Cureus 2020-09-09 /pmc/articles/PMC7546597/ /pubmed/33052294 http://dx.doi.org/10.7759/cureus.10333 Text en Copyright © 2020, Hayat et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Hayat, Muhammad Hashim Moazzam, Zorays Ziogas, Ioannis A Yousaf, Amman Hayat, Maham Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title | Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title_full | Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title_fullStr | Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title_full_unstemmed | Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title_short | Thyroid Storm Presenting as Acute Liver Failure in a Patient with Graves’ Disease |
title_sort | thyroid storm presenting as acute liver failure in a patient with graves’ disease |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546597/ https://www.ncbi.nlm.nih.gov/pubmed/33052294 http://dx.doi.org/10.7759/cureus.10333 |
work_keys_str_mv | AT hayatmuhammadhashim thyroidstormpresentingasacuteliverfailureinapatientwithgravesdisease AT moazzamzorays thyroidstormpresentingasacuteliverfailureinapatientwithgravesdisease AT ziogasioannisa thyroidstormpresentingasacuteliverfailureinapatientwithgravesdisease AT yousafamman thyroidstormpresentingasacuteliverfailureinapatientwithgravesdisease AT hayatmaham thyroidstormpresentingasacuteliverfailureinapatientwithgravesdisease |