Experimental and in silico evidence suggests vaccines are unlikely to be affected by D614G mutation in SARS-CoV-2 spike protein

The ‘D614G’ mutation (Aspartate-to-Glycine change at position 614) of the SARS-CoV-2 spike protein has been speculated to adversely affect the efficacy of most vaccines and countermeasures that target this glycoprotein, necessitating frequent vaccine matching. Virus neutralisation assays were perfor...

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Detalles Bibliográficos
Autores principales: McAuley, Alexander J., Kuiper, Michael J., Durr, Peter A., Bruce, Matthew P., Barr, Jennifer, Todd, Shawn, Au, Gough G., Blasdell, Kim, Tachedjian, Mary, Lowther, Sue, Marsh, Glenn A., Edwards, Sarah, Poole, Timothy, Layton, Rachel, Riddell, Sarah-Jane, Drew, Trevor W., Druce, Julian D., Smith, Trevor R. F., Broderick, Kate E., Vasan, S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546614/
https://www.ncbi.nlm.nih.gov/pubmed/33083031
http://dx.doi.org/10.1038/s41541-020-00246-8

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